You can specify an angle override that locks the cursor for the next point entered.
LINE command.
To specify an angle override, enter a left angle bracket (<) followed by an angle whenever a command asks you to specify a point. The command prompt sequence below shows a 30-degree override entered during aCommand: line
Specify first point: Specify a start point for the line
Specify next point or [Undo]: <30
Angle Override: 30
Specify next point or [Undo]: Specify a point
The angle you specify will lock the cursor, overriding Grid Snap, Ortho mode, and PolarSnap. Coordinate entry and object snaps have precedence over an angle override.